Fig. 5: Epithelial atrophy in HkNR cases. | Modern Pathology

Fig. 5: Epithelial atrophy in HkNR cases.

From: Characterization of initial/early histologic features of proliferative leukoplakia and correlation with malignant transformation: a multicenter study

Fig. 5

A Leukoplakia on the tongue dorsum and B biopsy that showed demarcated hyperkeratosis with epithelial atrophy (i.e., loss of tongue papillae; original magnification ×100) with minimal cytologic atypia (C original magnification ×400). D Homogenous proliferative leukoplakia of the upper right palatal gingiva. E Biopsy from D showed hyperkeratosis with minimal cytologic atypia present (original magnification ×400). F The leukoplakia in D developed a SCCa in 6 months (arrow). G Fissured leukoplakia of the left buccal mucosa, vestibule and buccal gingiva. H Biopsy from G showed hyperkeratosis with marked epithelial atrophy (original magnification ×100). I High-power view of H with minimal cytologic atypia (original magnification ×400).

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