Table 2 Risk profile changes.

From: Oropharyngeal cancer outcomes correlate with p16 status, multinucleation and immune infiltration

  

Fraction of patients

 

Pack-years

2000–2005

2006–2010

2011–2015

Tobacco exposure

<10

0.2

0.16

0.28

 

≥10

0.8

0.84

0.72

 

<30

0.36

0.28

0.49

 

≥30

0.64

0.72

0.51

 

Mean

44.39

45.46

32.16

 

Median

40

41.5

30

p16—clinical

Neg

0.68

0.48

0.36

 

Pos

0.32

0.52

0.64

p16—research

0–25

0.58

0.41

0.33

(% tumor cells with strong nuclear staining)

25–50

0.03

0.02

0.08

 

50–75

0.12

0.03

0.06

 

75–100

0.27

0.54

0.53