Table 3 Correlation between OP-TIL, IHC and risk factors.
From: Oropharyngeal cancer outcomes correlate with p16 status, multinucleation and immune infiltration
Mean | Mean | p-value | p-value | ||
|---|---|---|---|---|---|
OP-TIL (OS) | OP-TIL (DFS) | OP-TIL (OS) | OP-TIL (DFS) | ||
CD3/8 combined classifier | Cold | −0.98 | −0.14 | ||
Hot | −1.27 | −0.2 | <0.001 | <0.001 | |
p16 nuclear staining frequency | >70% | −1.23 | −0.18 | ||
<70% | −0.99 | −0.15 | <0.001 | <0.001 | |
Tobacco exposure (pack-years) | 0–10 | −1.26 | −0.19 | ||
10–30 | −1.1 | −0.17 | 0.022 | 0.221 | |
>30 | −1.04 | −0.15 | <0.001 | 0.003 |
