Fig. 3: Honeycomb change in UIP.
From: Usual interstitial pneumonia (UIP): a clinically significant pathologic diagnosis
Explanted lung from a 70-year-old man with a clinical diagnosis of IPF. A This section shows architectural distortion with extensive honeycomb change, manifesting as clusters of dilated, mucin-filled airspaces (short arrows). No normal lung architecture is identified. Compare honeycomb change (short arrows) with dilated airways (traction bronchiolectasis, long arrows). Note that honeycombing surrounds several airways. B Honeycomb change at high magnification. Dilated bronchus is at top. The honeycombed areas are filled with mucin (short arrows) and are lined by respiratory-type epithelium (arrowheads).
