Fig. 3: Eosinophilic vacuolated tumor (EVT).
From: Do we need an updated classification of oncocytic renal tumors?
A Grossly, EVT is solid, mahogany brown, and well-circumscribed tumor. B At low magnification, large vessels are invariably present at the periphery (lower left), with adjacent entrapped tubules, while a well-formed capsule is absent. C At low to medium power, EVT may superficially resemble chromophobe renal cell carcinoma. It has mostly solid architecture, often admixed with nested and tubulocystic areas (inset). D At high magnification, neoplastic cells have large intracytoplasmic vacuoles and round to oval nuclei with prominent nucleoli. E CD117 (KIT) is uniformly positive and only rare CK7 positive cells are present (inset), mimicking the immunoprofile of oncocytoma. F Cathepsin K and antimitochondrial antigen antibody (inset) are also positive in EVT.
