Fig. 1: Prototypic histomorphology and immunoprofile of study cases.
From: p53 null phenotype is a “positive result” in urothelial carcinoma in situ
H&E of large cell pleomorphic pattern urothelial carcinoma in situ (A, 200×). Paired p53 immunostains showing null phenotype pattern (complete loss of staining in lesional cells) (B, 200×). Paired positive keratin 20 staining in lesional cells (C, 200×) and negative CD44 staining in lesional cells (D, 200×).
