Fig. 4: Tile-level and slide-level results for withheld testing slides for clear cell sarcoma and rhabdomyosarcoma.

A Tile-level ROC curves and AUC scores of CCS, aRMS, and eRMS tiles in slide set withheld from model training. B Slide-level ROC curves and AUC scores of CCS, aRMS, and eRMS slide set withheld from model training. C Likelihood distributions resulting from CNN classification of tiles from pathologist-diagnosed CCS slides, with the top (All) representing softmax likelihood scores of all testing images, middle (CNN Agreement) representing likelihood distributions when pathologist diagnosis and softmax-assigned CNN diagnosis match, and bottom (CNN Misdiagnosis) represents likelihood distributions when pathologist diagnosis and softmax-assigned CNN diagnosis are mismatched. Minimum and median correct softmax tile scores were 0.3416 and 0.9252, respectively. D As per (C), but for tiles from pathologist-diagnosed aRMS slides. Minimum and median correct softmax tile scores were 0.4026 and 0.9130, respectively. E As per (C), but for tiles from pathologist-diagnosed eRMS slides. Minimum and median correct softmax tile scores were 0.3316 and 0.9191, respectively. F As per (C), but for pathologist-diagnosed CCS slides. Minimum and median correct softmax tile scores were 0.7095 and 0.8717, respectively. G As per (C), but for pathologist-diagnosed aRMS slides. Minimum and median correct softmax tile scores were 0.5025 and 0.8654, respectively. H As per (C), but for pathologist-diagnosed eRMS slides. Minimum and median correct softmax tile scores were 0.7095 and 0.6175, respectively.