Fig. 5: Distinct mutation rates in invasive LUAD subtypes. | Modern Pathology

Fig. 5: Distinct mutation rates in invasive LUAD subtypes.

From: Distinct mutational features across preinvasive and invasive subtypes identified through comprehensive profiling of surgically resected lung adenocarcinoma

Fig. 5

A The distinct mutation rates of the top six genes in various invasive LUAD subtypes including lepidic-predominant adenocarcinoma (LPA), acinar-predominant adenocarcinoma (APA), papillary-predominant adenocarcinoma (PPA), micropapillary-predominant adenocarcinoma (MPA), solid-predominant adenocarcinoma (SPA), and invasive mucinous adenocarcinoma (IMA). B Heat map illustrating the differential rates of the activating mutations involving the eight classic NSCLC oncogenes across the six major predominant invasive adenocarcinoma subtypes. The patients with fetal-, colloid-, and enteric-predominant subtypes were not included due to their limited sample size.

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