Fig. 5: The effect of DeepDx on the user test results. | Modern Pathology

Fig. 5: The effect of DeepDx on the user test results.

From: Artificial intelligence system shows performance at the level of uropathologists for the detection and grading of prostate cancer in core needle biopsy: an independent external validation study

Fig. 5

A The numbers of cases that the general pathologist’s diagnosis aligned with the reference standard (blue, n = 98 in total) or not (red, n = 52 in total) in the second round by following DeepDx. B The Gleason score (GS) distribution of the 52 discordant cases. Highlighted in yellow (GS 3 + 3) and green (GS 4 + 4) are the carcinomas recognized at first (no AI assistance) but missed at the second round (AI assistance). C One of the missed cancers with GS 3 + 3 (yellow in B) showed deceptively bland tumor glands (arrows; left). The GS 4 + 4 cancer (green in B) showed high-grade prostatic intraepithelial neoplasia-like architecture (arrows; right) with patchy stromal infiltration of poorly-formed glands (arrowheads; right) (original magnification, ×200; hematoxylin-eosin staining).

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