Table 1 Glossary of terms relevant to the diagnosis of HPVi(p53wt) vaVIN.
Term | Definition |
|---|---|
Acanthosis | Thickening of the epithelium with increased number of squamous layers Microscopically, thickening can be flat or accompany verruciform architecture |
Verruciform | In the shape of a verruca or wart, e.g., raised lesion with horn-like projections Microscopically, church-spire, horn or bulbous shaped epithelial projections, elongation and irregularity of the rete ridges |
Plaque | A broad-based elevated or raised area of the skin |
Epithelial pallor | Loss of epithelial eosinophilia in the superficial epidermal layers |
Hypogranulosis | Loss of the granular cell layer in the epidermis, patchy or diffuse |
Hypergranulosis | Increase in the thickness of the granular cell layer in the epidermis |
