Fig. 2: Diffuse mesothelioma with superficial areas mimicking well differentiated papillary mesothelial tumor.
From: Well differentiated papillary mesothelial tumor: a new name and new problems

A, B Two different areas of an ordinary invasive diffuse mesothelioma in which there are superficial expansile papillae with myxoid cores. A shallow biopsy might sample only the papillary area, leading to a misdiagnosis of well differentiated papillary mesothelial tumor. Review of the operator’s report can be very helpful in this situation if the description is that of a diffuse serosal malignancy.