Fig. 2: Chromophobe RCC. | Modern Pathology

Fig. 2: Chromophobe RCC.

From: Low grade oncocytic tumors of the kidney: a clinically relevant approach for the workup and accurate diagnosis

Fig. 2

Chromophobe RCC is best classified based on classic histologic features that include (A, B) irregular nuclear membranes and perinuclear clearing. Features of “borderline” or “difficult to classify” low grade oncocytic tumors, which we designate as “oncocytic renal neoplasm of low malignant potential”, include (C) more variability in nuclear size without the irregular nuclear membranes typical of chromophobe RCC, D often with more irregular chromatin distribution.

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