Fig. 1: Overview of tumor purity estimations assessed by pathological evaluation based on histology, and four methylation-based methods; InfiniumPurify25,26, PAMES27, RF_absolute and RF_estimate28.

Left; IDH-mutant glioma, middle; glioblastoma IDH-wildtype and right; meningioma. Each bar represents one biopsy and the biopsies for each patient are grouped together. Not analyzed tumor biopsies are marked with an X. The dashed line represents tumor purity of 70%.