Fig. 6: SBS38, SBS6, and genome instability are associated with poor prognosis in melanoma. | Modern Pathology

Fig. 6: SBS38, SBS6, and genome instability are associated with poor prognosis in melanoma.

From: Comprehensive genomic analysis of primary malignant melanoma of the esophagus reveals similar genetic patterns compared with epithelium-associated melanomas

Fig. 6

A Patients with PMME with a high proportion of SBS38 experienced shorter OS times than the remaining patients with a lower proportion of SBS38. B Patients with PMME with a high proportion of SBS6 experienced worse RFS outcomes than the remaining patients with a lower proportion of SBS6. C The patients with PMME were divided into a high GIIAmp group and a low GIIAmp group, and the high GIIAmp group showed a significantly shorter OS duration than the low GIIAmp group. D Patients with SKCM with a high proportion of SBS38 had a shorter OS duration than those without or with a low proportion of SBS38. E Patients with SKCM with high GIIAmp tended to have a shorter OS time, although the difference was not significant. A–E The number of patients (n) per group is indicated.

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