Table 1 Clinical, gross, and histologic characteristics of tested CPAMs.
KRAS mutation | c.35 G > A; p.G12D | c.35 G > T; p.G12V | c.34 G > C; p.G12R | c.34 G > T; p.G12C | c.29_31dupGGA; p.G10dup | Wild type | p value |
|---|---|---|---|---|---|---|---|
Total number of patients | 53 | 21 | 4 | 2 | 1 | 8 | |
Gross size of largest cyst (mean ± SD, range) | 3 ± 1.5 cm (0.5–6.0) | 2.7 ± 1.7 cm (0–6.5) | 3.4 ± 1.8 (1.2–5.5) | 1.9 ± 2.6 (0–3.7) | 0 | 0.7 ± 0.8 (0–2.5) | 3 × 10−3 a |
Lesions with MCCs | 43 (81%) | 16 (76%) | 3 (75%) | 1 (50%) | 1 (100%) | 0 | 8.4 × 10−5 b |
Histologic category | |||||||
Type 1 | 48 (91%) | 8 (38%) | 0 | 1 (50%) | 0 | 1 (13%) | |
Type 1/3 | 5 (9%) | 9 (43%) | 4 (100%) | 0 | 0 | 1 (13%) | |
Type 3 | 0 | 4 (19%) | 0 | 1 (50%) | 1 (100%) | 6 (75%) | 8.4 × 10−12 b |
