Fig. 5: Sclerosing paratesticular rhabdomyoma reclassified as cellular fetal-type. | Modern Pathology

Fig. 5: Sclerosing paratesticular rhabdomyoma reclassified as cellular fetal-type.

From: Molecular assessment of paratesticular rhabdomyomas demonstrates recurrent findings, including a novel H3C2 p.K37I mutation

Fig. 5

A, B Case 7 was originally diagnosed as a sclerosing rhabdomyoma. DNA sequencing identified multiple chromosome-level and arm-level copy number gains in this case, which were not seen in other sclerosing rhabdomyomas. In light of the molecular findings, slides were re-reviewed demonstrating that this tumor was significantly more cellular and had a more prominent fascicular arrangement than the rest of the sclerosing rhabdomyomas (compare to Fig. 1). Therefore, this tumor was reclassified as cellular fetal rhabdomyoma with sclerotic stroma.

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