Fig. 4: Cluster-based representation of transcriptome analysis.

A Heatmap showing similar statistically significant transcriptomic profiles among the clusters identified in the current study with the existing molecular subgroups of pancreatic ductal adenocarcinoma (Moffit’s, Collisson’s, and Bailey’s subgroups); B Activation of different biological mechanisms in the three clusters. Statistically significant values are shown. C Heatmap of the immune subpopulations inferred by gene expression of immune-related metagenes significantly enriched in any of the three clusters.