Table 1 Summary of the most important clinicopathologic data of pancreatic ITPNs and concomitant invasive adenocarcinomas.
N case | Sex, age | Site in the pancreas | Associated cancer | Size of the whole lesion (invasive component) | pTNM (T = size of the invasive component) | Tumor stage | VI | PNI | R | Involved ducts | Relevant clinical history and symptoms | Main radiologic findings | Survival (months) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | M, 76 | Head-body-tail | Yes | 100 mm (25 mm) | pT2N1M0 | IIB | Yes | No | R0 | Main + branch | Abdominal pain | Solid-cystic lesion | AF (65) |
2 | F, 71 | Head | No | 20 mm | pTisN0M0 | 0 | n/a | n/a | R0 | Main | Incidental finding | Solid-cystic lesion | AF (62) |
3 | M, 68 | Head | Yes | 50 mm (36 mm) | pT2N1M0 | IIB | Yes | No | R0 | Main + branch | Jaundice | Solid-cystic lesion | AF (31) |
4 | F, 75 | Head, body, tail | Yes | 130 mm (60 mm) | pT3N0M0 | IIA | no | No | R1 | Main + branch | Abdominal pain | Solid-cystic lesion | DO (0) |
5 | M, 72 | Head | No | 12 mm | pTisN0M0 | 0 | n/a | n/a | R0 | Main | Jaundice | Solid-cystic lesion | AF (15) |
6 | F, 50 | Head-body-tail | No | 36 mm | pTisN0M0 | 0 | n/a | n/a | R0 | Main + branch | Epigastric pain, steatorrhea, weight loss | Enlargement of the pancreatic gland, Solid-cystic | AF (54) |
7aa | M, 57 | Tail | No | 16 mm | pTisN0M0 | 0 | n/a | n/a | R0 | Main | Acute pancreatitis | Cystic lesion | AD (38) |
7ba | M, 59 | Head-body | Yes | 25 mm (12 mm) | pT1cN0M0 | IA | Yes | Yes | R0 | Main + branch | Diagnosed on follow-up for ITPN | Solid-cystic | AF (8) |
8 | F, 64 | Body-tail | Yes | 70 mm (23 mm) | pT2N1M0 | IIB | Yes | Yes | R0 | Main + branch | Abdominal pain | Solid-cystic | AF (9) |
9 | M, 60 | Body-tail | Yes | 60 mm (31 mm) | pT2N0M0 | IB | Yes | Yes | R0 | Main + branch | Peutz–Jeghers syndrome; Diagnosed on follow-up | Solid-cystic | AF (27) |
10 | F, 47 | Body | Yes | 25 mm (3 mm) | pT1aN0M0 | IA | No | No | R0 | Main | n/a | Solid lesion | AF (3) |
11 | F, 63 | Head | Yes | 35 mm (22 mm) | pT2N2M0 | III | Yes | Yes | R0 | Main | Jaundice, pruritus | Solid lesion | AD (54); liver metastasis (9) |
12 | F, 60 | Body-tail | Yes | 90 mm (45 mm) | pT3N2M0 | III | Yes | Yes | R0 | Main | Fatigue, weight loss, fever, abdominal pain | Solid lesion | DD (2); recurrence (1) |
13 | F, 72 | Head | Yes | 25 mm (7 mm) | pT1bN2M0 | III | Yes | Yes | R0 | Main | Epigastric pain, weight loss, anorexia | Solid lesion | n/a |
14 | F, 59 | Head | Yes | 25 mm (9 mm) | pT1bN0M0 | IA | Yes | Yes | R0 | Main | Previous ovarian serous carcinoma | Solid lesion | DO (21) |
15 | F, 64 | Head-body-tail | Yes | 66 mm (4 mm) | pT1aN0M0 | IA | Yes | Yes | R0 | Main + branch | Abdominal pain | Solid-cystic | DO (13) |
16 | F, 54 | Body-tail | Yes | 35 mm (30 mm) | pT2N2M1 | IV | Yes | Yes | R1 | n/a | Dyspepsia, abdominal pain | Solid-cystic | AF (4) |
