Fig. 2: Co-occurring genomic alterations in SMARCB1-deficient sarcomas. | Modern Pathology

Fig. 2: Co-occurring genomic alterations in SMARCB1-deficient sarcomas.

From: The genetic landscape of SMARCB1 alterations in SMARCB1-deficient spectrum of mesenchymal neoplasms

Fig. 2

A Oncoprint showing recurrent, clinically significant (by OncoKB annotation) co-occurring genetic alterations in SMARCB1-deficient sarcomas and their corresponding histotypes. TMB: tumor mutation burden. B Oncoprint showing acquisition of co-occurring mutations or copy number alterations in subsequent recurrence or metastases among proximal-type epithelioid sarcoma and their SMARCB1 genetic alterations (copy number, loss-of-function mutations). This plot only included cases with SMARCB1 deletion detected by sequencing but not those detected by FISH.

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