Table 1 Patient-, procedure-, basic tumor characteristics, and tumor morphology in association with the relationship of tumor cells to the free peritoneal surface in micrometers (µm).
Total (n = 189) | Full peritoneal penetration (n = 89) | 0–99 µm to peritoneum (n = 34) | 100–999 µm to peritoneum (n = 33) | ≥1000 µm to peritoneum (n = 33) | p value | |
---|---|---|---|---|---|---|
Patient characteristics | ||||||
Age <70 | 164 (87) | 77 (87) | 32 (94) | 23 (70) | 32 (97) | 0.005 |
Age >70 | 25 (13) | 12 (13) | 2 (6) | 10 (30) | 1 (3) | |
Gender, male | 101 (53) | 51 (57) | 15 (44) | 17 (52) | 18 (55) | 0.618 |
Received adjuvant chemotherapy | 168 (89) | 81 (91) | 32 (94) | 26 (79) | 29 (88) | 0.204 |
Received adjuvant HIPEC | 105 (56) | 54 (61) | 18 (53) | 15 (45) | 18 (55) | 0.486 |
Basic tumor and procedure characteristics | ||||||
Tumor location | ||||||
Appendix | 4 (2) | 4 (4) | 0 (0) | 0 (0) | 0 (0) | - |
Cecum | 37 (20) | 12 (13) | 1 (3) | 7 (21) | 7 (21) | |
Ascending colon and hepatic flexure | 26 (14) | 18 (20) | 4 (12) | 3 (9) | 1 (3) | |
Transverse colon | 12 (6) | 9 (10) | 1 (3) | 1 (3) | 1 (3) | |
Splenic flexure and descending colon | 16 (8) | 8 (9) | 2 (6) | 3 (9) | 3 (9) | |
Sigmoid colon | 90 (48) | 34 (38) | 16 (47) | 19 (58) | 21 (64) | |
Procedure type | ||||||
(Extended) right hemicolectomy | 71 (38) | 39 (44) | 15 (44) | 10 (30) | 7 (21) | 0.130 |
(Extended) left hemicolectomy | 25 (13) | 14 (16) | 3 (9) | 4 (12) | 4 (12) | |
Sigmoid resection | 62 (33) | 19 (21) | 11 (32) | 14 (42) | 17 (51) | |
Subtotal colectomy | 4 (2) | 2 (2) | 0 (0) | 1 (3) | 1 (3) | |
Anterior resection | 27 (14) | 15 (17) | 5 (15) | 4 (12) | 3 (9) | |
Multivisceral resection | 67 (35) | 13 (15) | 11 (32) | 20 (61) | 23 (70) | <0.001 |
Elective resection | 154 (81) | 68 (77) | 32 (94) | 27 (82) | 27 (82) | 0.163 |
Completed laparoscopic primary tumor resection | 103 (55) | 58 (65) | 21 (62) | 14 (42) | 10 (30) | 0.008 |
Converted laparoscopic primary tumor resection | 19 (10) | 8 (9) | 4 (12) | 4 (12) | 3 (9) | |
Open primary tumor resection | 67 (35) | 23 (26) | 9 (26) | 15 (45) | 20 (61) |