Table 1 Patient-, procedure-, basic tumor characteristics, and tumor morphology in association with the relationship of tumor cells to the free peritoneal surface in micrometers (µm).

From: The measured distance between tumor cells and the peritoneal surface predicts the risk of peritoneal metastases and offers an objective means to differentiate between pT3 and pT4a colon cancer

 

Total (n = 189)

Full peritoneal penetration (n = 89)

0–99 µm to peritoneum (n = 34)

100–999 µm to peritoneum (n = 33)

≥1000 µm to peritoneum (n = 33)

p value

Patient characteristics

 Age <70

164 (87)

77 (87)

32 (94)

23 (70)

32 (97)

0.005

 Age >70

25 (13)

12 (13)

2 (6)

10 (30)

1 (3)

 Gender, male

101 (53)

51 (57)

15 (44)

17 (52)

18 (55)

0.618

 Received adjuvant chemotherapy

168 (89)

81 (91)

32 (94)

26 (79)

29 (88)

0.204

 Received adjuvant HIPEC

105 (56)

54 (61)

18 (53)

15 (45)

18 (55)

0.486

Basic tumor and procedure characteristics

Tumor location

  Appendix

4 (2)

4 (4)

0 (0)

0 (0)

0 (0)

-

  Cecum

37 (20)

12 (13)

1 (3)

7 (21)

7 (21)

  Ascending colon and hepatic flexure

26 (14)

18 (20)

4 (12)

3 (9)

1 (3)

  Transverse colon

12 (6)

9 (10)

1 (3)

1 (3)

1 (3)

  Splenic flexure and descending colon

16 (8)

8 (9)

2 (6)

3 (9)

3 (9)

  Sigmoid colon

90 (48)

34 (38)

16 (47)

19 (58)

21 (64)

Procedure type

  (Extended) right hemicolectomy

71 (38)

39 (44)

15 (44)

10 (30)

7 (21)

0.130

  (Extended) left hemicolectomy

25 (13)

14 (16)

3 (9)

4 (12)

4 (12)

  Sigmoid resection

62 (33)

19 (21)

11 (32)

14 (42)

17 (51)

  Subtotal colectomy

4 (2)

2 (2)

0 (0)

1 (3)

1 (3)

  Anterior resection

27 (14)

15 (17)

5 (15)

4 (12)

3 (9)

  Multivisceral resection

67 (35)

13 (15)

11 (32)

20 (61)

23 (70)

<0.001

  Elective resection

154 (81)

68 (77)

32 (94)

27 (82)

27 (82)

0.163

  Completed laparoscopic primary tumor resection

103 (55)

58 (65)

21 (62)

14 (42)

10 (30)

0.008

  Converted laparoscopic primary tumor resection

19 (10)

8 (9)

4 (12)

4 (12)

3 (9)

  Open primary tumor resection

67 (35)

23 (26)

9 (26)

15 (45)

20 (61)

  1. ASA-score American Society of Anesthesiologists score, HIPEC hyperthermic intraperitoneal chemotherapy.
  2. Bold values indicate a statistical significant difference (p < 0.05).