Table 3 Association between clinicopathological parameters and the crude proportion of patients who developed peritoneal metastases (PM).
No PM N (%) | PM N (%) | p value | |
|---|---|---|---|
Tumor & histopathological characteristics | |||
Tumor location | |||
Right sided | 58 (73.4) | 21 (26.6) | 0.079 |
Left sided | 89 (84.0) | 17 (16.0) | |
Type and differentiation | |||
Well/moderately differentiated adenocarcinoma | 112 (83.0) | 23 (17.0) | 0.122 |
Poorly differentiated adenocarcinoma | 17 (73.9) | 6 (26.1) | |
Mucinous carcinoma | 16 (80.0) | 4 (20.0) | |
Signet ring cell carcinoma | 6 (54.5) | 5 (45.5) | |
Tumor border configuration | |||
Pushing | 49 (89.1) | 6 (10.9) | 0.043 |
Infiltrating | 102 (76.1) | 32 (23.9) | |
Tumor budding | |||
Low budding (Bd1) | 57 (86.4) | 9 (13.6) | 0.261 |
Intermediate budding (Bd2) | 21 (75.0) | 7 (25.0) | |
High budding (Bd3) | 73 (76.8) | 22 (23.2) | |
Tumor-stroma ratio | |||
Stroma-low (≤50% stroma) | 66 (78.6) | 18 (21.4) | 0.685 |
Stroma-high (>50% stroma) | 85 (81.0) | 20 (19.0) | |
Venous invasion | 77 (77.0) | 23 (23.0) | 0.293 |
Lymphatic invasion | 55 (70.5) | 23 (29.5) | 0.007 |
Perineural invasion | 75 (72.8) | 28 (27.2) | 0.008 |
Lymph node status | |||
pN0 | 42 (84.0) | 8 (16.0)0 | 0.118 |
pN1 (1–3 positive nodes) | 57 (85.1) | 10 (14.9) | |
pN2 (4+ positive nodes) | 52 (72.2) | 20 (27.8) | |
Tumor deposits | 45 (83.3) | 9 (16.7) | 0.456 |
Irradical resection (R1) | 19 (76.0) | 6 (24.0) | 0.602 |
pT4b | 28 (80.0) | 7 (20.0) | 0.986 |
Distance from tumor to free peritoneal surface in micrometers (um) | |||
Full peritoneal penetration of tumor cells onto the peritoneal surface | 67 (75.3) | 22 (24.7) | 0.038 |
Shortest distance to free peritoneal surface 0–99 µm | 24 (70.6) | 10 (29.4) | |
Shortest distance to free peritoneal surface 100–999 µm | 31 (93.9) | 2 (6.1) | |
Shortest distance to free peritoneal surface ≥1000 µm | 29 (87.9) | 4 (12.1) | |
