Table 3 Gamma knife models, doses, and targets selected in various gamma knife capsulotomy studies
From: Evolution of gamma knife capsulotomy for intractable obsessive-compulsive disorder
Study | Technique | Gamma Knife Model | No. of patients | Dose, Gy (N of targets) | No. of isocenters (N) | Dorsal-ventral extension in internal capsule | Collimators, mm (N of patients) | Reoperations |
|---|---|---|---|---|---|---|---|---|
Gamma Knife capsulotomy | GK I (first prototype) | 21 | 80 (2) 100 (2) 120 (4) 140 (4) 152(2) 160 (25) 170(1) 180(2) | 1 | Midcapsular | 3 × 5 mm (14) 3 × 11(7) | 3 | |
Gamma Knife capsulotomy | GK II (second prototype) | 3 | 100 (1) 120(1) 160(4) | 1 | Midcapsular | 4 mm (1) 8 mm (2) | 1 | |
Kihlström et al. [63] | Gamma Knife capsulotomy | B | 11 | 160 (2), 200 (9) | 1 (1), 3 (9), 4 (1) | Midcapsular and Dorsal, mid and ventralcapsular | 4 (10), 8 (1) | 1 |
Rasmussen et al. [125] | Gamma ventral capsulotomy, single and double-shots | U | 15 | 180 (35) | 1 (first 15 pt.), 2 (13 of the first 15 pt) | Midcapsular (first 15 pt.), mid and ventralcapsular (13) | 4 (15) | 13 of the first 15 pt. added a second ventral lesion |
Lopes et al. [69] | Gamma ventral capsulotomy, double-shot | B | 5 | 180 | 2 | Mid and ventralcapsular | 4 (5) | None |
Kondziolka et al. [78] | Gamma ventral capsulotomy, double-shot | NA | 3 | 140 (2), 150 (1) | 2 | Mid and ventralcapsular | 4 (3) | None |
Sheehan et al. [79] | Gamma ventral capsulotomy, single-shot | Perfexion | 5 | 140 (3), 160 (2) | 1 (ventralcapsular) | Ventralcapsular | 4 (5) | None |
Lopes et al. [25] | Gamma ventral capsulotomy, double-shot | B | 12 | 4 (40) | 2 (12) | Mid and ventralcapsular | 4 (12) | None |
Peker et al. [126] | Gamma ventral capsulotomy, single and double-shots | C (1) and Perfexion (9) | 10 | 140, 150 | 1 (2), 2 (8) | NA | 4 (10) | NA |
Rasmussen et al. [77] | Gamma ventral capsulotomy, single and double-shots | U (37) and C (18) | 55 | 180 (55) | 1 (first 15 pt.), 2 (13 of the first 15 pt, reoperated); 2 (40 additional pt) | Mid and ventralcapsular | 4 (55) | 13 of the first 15 pt. added a second ventral lesion |
