Fig. 5
From: Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism
Antibiotic treatment ameliorates HFD-induced inflammation in the nucleus accumbens (Nacc). a mRNA abundance measured by RT qPCR in the Nacc of chow and HFD-fed mice, treated or not with antibiotics (n = 12/group). b ELISA assays for IL-1β and TNFα present in homogenates from the Nacc (n = 14/group). c Representative images of the Nacc from chow and HFD-fed mice treated or not with antibiotics, stained with Cd11b antibody (red). Scale bars, 200 μm. C chow, H HFD, M HFD + metronidazole, V HFD + vancomycin. Data are shown as mean ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001 by ANOVA, followed by pre-planned t-tests
