Table 1 Summary of the phenotypic models in the 48 individuals from the t(1;11) family

From: DNA sequence-level analyses reveal potential phenotypic modifiers in a large family with psychiatric disorders

Model

Diagnoses

Affected

Controls

NA

T-aff

NT-aff

mtLOD

t(1;11)

Model A

SCZ, BD, SCZAFF

6

23

19

6

0

3.2

2.8

Model B

SCZ, BD, SCZAFF, rMDD, cyclothymia

15

23

10

13

2

8.6

6.7

Model C

SCZ, BD, SCZAFF, rMDD, cyclothymia, MDD, adolescent conduct disorder, generalised anxiety disorder, alcoholism

24

23

1

18

6

12

5.8

Model D

MDD, adolescent conduct disorder, generalised anxiety disorder, alcoholism

9

23

16

5

4

5.8

1.3

Model E

SCZ, BD, SCZAFF, rMDD

12

23

13

10

2

6.9

4.8

Model F

BD, rMDD, MDD

14

23

11

9

5

8.9

4.2

Model G

BD, rMDD

8

23

17

6

2

5.7

3.1

Model H

SCZ, SCZAFF

4

23

21

4

0

2.4

2.2

Psychosis

Psychosis any diagnosis

8

23

17

8

0

4.4

1.9

Total

 

24

23

1

19

29

  
  1. mtLOD, maximum theoretical LODs; t(1;11), the two-point LOD score for the translocation; number of affected translocation carriers (T-aff) and affected non-carriers (NT-aff), further details are given in Supplementary Table 2
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