Table 2 Summary of multipoint and two-point linkage analyses
Region | Start | End | Size | Max mLOD | Model | N genes | Max 2pt LOD | Model | Top 2pt variant | Closest gene distance |
|---|---|---|---|---|---|---|---|---|---|---|
chr1q | 223,246,661 | 224,932,082 | 1,685,421 | 5.6 | B | 14 | 9.3 | C | chr1: 223,804,982 | [CAPN8] intronic |
chr5q | 58,721,609 | 67,098,280 | 8,376,671 | 3.5 | F | 33 | 5.1 | F | rs377870 | [C5orf64] intronic |
chr11q1 | 87,597,790 | 88,350,687 | 752,897 | 5.9 | C | 3 | 10.8 | C | chr11: 88,219,524 | []GRM5 18,221 bp |
chr11q2 | 99,616,360 | 99,753,867 | 137,507 | 3.7 | F | 1 | 8.5 | F | chr11: 99,653,622 | [CNTN5] intronic |
chr1p | 69,000,000 | 71,000,000 | 2,000,000 | 2.2 | F | 7 | 2.3 | F | rs149129136 | []LRRC7 151,267 bp |
chr2p | 17,768,000 | 18,351,000 | 583,000 | 2.3 | P | 5 | 2.3 | E | rs4832502 | []KCNS3 24,483 bp |
chr3q | 162,000,000 | 172,000,000 | 10,000,000 | 2.3 | F | 36 | 3.6 | C | chr3: 164,306,631 | []SI 390,056 bp |
chr4q | 158,000,000 | 164,000,000 | 6,000,000 | 2.2 | F | 15 | 3.6 | F | rs149639769 | []FSTL5 1,432,353 bp |
chr16p | 16,000,000 | 33,000,000 | 17,000,000 | 2.6 | G | 222 | 3.4 | G | chr16: 23,353,022 | [SCNN1B] intronic |
