Table 1 Demographic table for early psychosis patients and healthy controls enrolled in the study

From: MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients

 

Controls (n = 68/39)

Patients (n = 111/33)

p-value

Age (years, mean ± s.d.)

25.3 ± 4; 25.08 ± 4.7

24.4 ± 4; 23.9 ± 4.7

0.133a 0.27a

Gender

43 men; 25 women

84 men; 27 women

0.09b

 

20 men; 19 women

24 men; 9 women

0.08b

Cigarette users/non-users

8/54; 6/29

41/39; 15/18

< 0.001b; 0.017b

BMI (kg/m2, means ± s.d.)

23.03 ± 2.9; 22.57 ± 2.5

24.1 ± 3.6; 23.5 ± 3.3

0.06a; 0.19a

GAG-GCL polymorphism (LR/HR)

47/21; 25/14

77/34; 21/12

1b; 1b

Illness duration (years, mean ± s.d.)

NA

2 ± 1.8; 2 ± 1.7

NA

CPZ equivalent (mg, mean ± s.d.)

NA

337.9 ± 276.4; 385.1 ± 316.5

NA

  1. CPZ equivalents chlorpromazine equivalents, n.s. not significant (P > 0.05), LR low risk, HR high risk
  2. In italics: subjects with a magnetic resonance spectroscopy (MRS) scan
  3. at-test
  4. bFisher exact test