Fig. 2

Results of meta- and mega-analyses including nine independent datasets from the ENIGMA-22q11DS working group. The bar graphs on the left side are organized based on the effect sizes for FA (positive to negative, from left to right). The brain maps on the right side are organized by rows, each one corresponding to respective bar graph on the left. These show the JHU-ICBM atlas white matter ROIs that passed multiple comparisons correction after meta-analysis. The model tested was: DTI-ROI-measure = ß0 + ß1Diagnosis + ß2Sex + ß3Age + ß4Age2centered. WM: Average of all white matter JHU-ICBM ROIs