Fig. 4 | Molecular Psychiatry

Fig. 4

From: Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study

Fig. 4

Comparison of effect sizes in this study, to those from the ENIGMA-Schizophrenia DTI Working Group using similar methods (2359 healthy controls vs 1963 schizophrenia patients from 29 independent studies; Kelly et al. [40]; blue triangles) to 22q11DS probands with and without psychosis (red circles). Positive effect sizes: 22q-Psychosis > 22q-No psychosis OR schizophrenia patients > healthy controls. Negative effect sizes: 22q-No psychosis > 22q-psychosis OR healthy controls > schizophrenia patients. We note, as stated in the ENIGMA-DTI protocol [38], that the IFO and UNC in the original JHU atlas from FSL, were later renamed the UNC and TAP, respectively. Here we matched the ENIGMA-Schizophrenia results with the updated atlas

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