Fig. 8 | Molecular Psychiatry

Fig. 8

From: MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties

Fig. 8

miR-298 reduces two specific isoforms of total tau protein. a Western blotting from a mixed-brain cell type human primary culture is shown. (n = 4). b Total tau showed no significant differences by treatment. c Treatment with miR-298 associated with a significant reduction of a ~55 kDa band. d Treatment with miR-298 also produced significant differences for a 50 kDa band. e Treatment with miR-298 produced no significant differences for a 48 kDa band. Pairwise differences (p ≤ 0.05) are indicated by letters. Treatments sharing a letter did not significantly differ.

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