Table 1 Sample clinical and demographic characteristics showing that there were no group differences between healthy volunteers and first episode psychosis patients in age, sex, ethnicity, socio-economic status, body mass index, cannabis, alcohol or tobacco use.

From: The neural and molecular basis of working memory function in psychosis: a multimodal PET-fMRI study

 

Healthy volunteers

First episode psychosis patients

t/x2/U

df

p

N

35

31

   

Age mean (SD), years

27.12 (5.32)

26.64 (4.68)

t = 0.52

64

0.60

Sex (male/female)

26/9

26/5

x2 = 1.18

2

0.55

Ethnicity (Caucasian/Black African or Black Caribbean/ Asian/ Mixed/missing)

15/3/11/4/2

12/0/6/3/0

x2 = 8.49

6

0.20

Years of education after compulsory education mean (SD)a

4.01 (3.81)

3.01 (2.59)

t = 1.63

58

0.11

Socio-economic status (high/medium/ low/unemployed/ student/missing data)b

3/4/10/1/13/4

1/2/13/5/7/3

x2 = 24.38

20

0.23

Body mass index mean (SD) score

25.12 (3.81)

25.65 (5.10)

t = −0.41

46

0.68

Current cannabis use (yes/no)

0/35

0/31

NA

NA

NA

Current alcohol use (yes/no/missing data)

21/12/2

17/13/1

x2 = 2.88

4

0.60

Current tobacco use (yes/no/ missing data)

10/23/2

13/17/1

x2 = 3.14

4

0.53

Diagnosis (schizophrenia/ schizoaffective disorder)

NA

28/3

NA

NA

NA

Illness duration mean (SD), months

NA

22.39 (12.80)

NA

NA

NA

Duration of prior treatment mean (SD), months

NA

6.16 (10.10)

NA

NA

NA

Current use of antipsychotics (yes/no)

NA

31/0

NA

NA

NA

Prior use of antipsychotics (yes/no)

NA

23/8

NA

NA

NA

PANSS positive mean (SD) score

NA

25.83 (14.90)

NA

NA

NA

PANSS negative mean (SD) score

NA

24.10 (7.53)

NA

NA

NA

PANSS general mean (SD) score

NA

40.45 (10.20)

NA

NA

NA

PANSS total mean (SD) score

NA

86.82 (21.83)

NA

NA

NA

  1. N sample size, SCZ schizophrenia, SCZA schizoaffective disorder, PANSS Positive and Negative Syndrome scale, t (independent samples t-test), x2 (chi-square test), degrees of freedom (df), NA not applicable, SD standard deviation
  2. aYears of education: calculated as the years of education after compulsory education (minimum compulsory education in the United Kingdom is 12 years)
  3. bSocio-economic status: High = high, intermediate and lower grade professionals; medium = small employer, self-employed and lower technical occupations; low = sales, routine occupations, unemployed; student = student