Fig. 3: The variance (y-axis) of case-control status explained by the PRS-SZBD and PRS-MDD in Archetypal and Atypical MPDs. | Molecular Psychiatry

Fig. 3: The variance (y-axis) of case-control status explained by the PRS-SZBD and PRS-MDD in Archetypal and Atypical MPDs.

From: Identifying and validating subtypes within major psychiatric disorders based on frontal–posterior functional imbalance via deep learning

Fig. 3

x-axis represents p value threshold, y-axis represents PRS model fit: R2 (Nagelkerke’s). The bars represent ten best-fit PRS scores calculated at different p value threshold. ***p < 0.001; **p < 0.01. PRS-SZBD, polygenetic risk score of schizophrenia and bipolar disorder, PRS-MDD, polygenetic risk score of major depressive disorder. MPD major psychiatric disorder.

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