Fig. 2: Volcano plots of DNA methylation association with AUD.

Volcano plots depicting the effect sizes of DNA methylation association with AUD (x axis) as a function of the negative natural log of the p value (y axis) for the discovery (a) and replication (b) cohorts. Red dashed horizontal line depicts a nominal p value of 0.05. c Scatter plot showing the relationship between module membership of probes (x axis) versus associations with AUD status (y axis).