Fig. 6: Replication of the outcomes associated with the three clinical profiles.
From: Topology predicts long-term functional outcome in early psychosis
a Table summarizing the retained diagnoses of patients in the validation cohort. The Chi-Square test for independence indicates a difference between groups in the proportion of diagnosis. Brief Ep.: brief psychotic episode. b Bar graph illustrating the percentage of patients in the validation cohort from predicted groups A, B, and C who are working, living independently, or in symptomatic remission, and the score for the SOFAS and GAF scales. *p < 0.05. c Precision-recall curve of Logistic Regression, with regularization strength 1, when using PANSS items (red), TDA-based group membership (blue), k-means clustering (purple), or k-means clustering on PCA (green). The dashed line represents the proportion of patients with good outcome in cohort 2, i.e., the precision of the model that always predicts good outcome.
