Table 1 Demographic and clinical characteristics of participants.

From: Neuroinflammation as measured by positron emission tomography in patients with recent onset and established schizophrenia: implications for immune pathogenesis

 

Recent

Established

Recent vs ES

Characteristics

Controls (n = 10)

Patients (n = 20)

p

Controls (n = 11)

Patients (n = 21)

p

p

Sex (M)

8 (80%)

14 (70%)

–

7 (64%)

13 (62%)

–

–

Age (years)

25.5 ± 4.1

24.2 ± 5.1

0.48

46.7 ± 4.8

46.3 ± 6.4

0.85

0.000*

BMI (kg/m2)

26.5 ± 3.6

24.7 ± 3.6

0.19

26.6 ± 5.2

29.5 ± 5.3

0.15

0.002*

Smoking (Yes)

4 (40%)

17 (85%)

–

2 (18%)

15 (71%)

–

–

Duration of illness (months)

–

16 ± 17

–

–

249 ± 88

–

0.000*

PANSS total

–

57 ± 12

–

–

55 ± 13

–

0.74

PANSS positive

–

15 ± 6

–

–

15 ± 7

–

0.92

PANSS negative

–

12 ± 4

–

–

13 ± 5

–

0.53

PANSS general

–

30 ± 6

–

–

27 ± 6

–

0.22

PSP

–

59 ± 14

–

–

53 ± 15

–

0.14

Injected mass of PK11195 (μg)

1.39 ± 0.63

1.86 ± 1.72

0.29

1.28 ± 0.66

1.22 ± 0.91

0.84

0.15

  1. Values are presented as mean ± SD.
  2. BMI body mass index, PANSS positive and negative syndrome scale, PSP personal and social performance scale.
  3. *Significant difference between groups at p ≤ 0.05.
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