Fig. 3: Gene expression alteration observed in response to the absence of 6′SL from maternal milk and/or due to the absence of the St6Gal1 gene. | Molecular Psychiatry

Fig. 3: Gene expression alteration observed in response to the absence of 6′SL from maternal milk and/or due to the absence of the St6Gal1 gene.

From: Sialylated human milk oligosaccharides program cognitive development through a non-genomic transmission mode

Fig. 3

a Circle plot presenting some of the pathways regulated by differentially expressed genes. The red boxes in the middle show the z-score, which is a normalized count of the number of up- or downregulated genes. The outer circle shows a scatter plot of the logFC for each of the assigned genes. The red and blue points represent over or under expression of the genes involved in each pathway. b Heatmap of 61 differentially expressed genes. Each cell represents the normalized log2 expression of each gene in each sample. Each row is a gene, each column is a sample. Dendrogram were obtained using hierarchical clustering with complete linkage on both features and samples. Samples are colored according to their group (milk or control) (Color figure online).

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