Fig. 5: Fear extinction is facilitated by PBM early interventions.
From: Photobiomodulation prevents PTSD-like memory impairments in rats
A Rats were conditioned on days 1–2 in context-A, followed by extinction training on days 3–6 in context-B. B PBM exhibited no treatment effect on fear extinction when PBM was applied immediately after extinction training (n = 10 each). C Extinction was facilitated when PBM was administered immediately after conditioning on days 1 and 2 (Res & PBM, n = 9 each). D This facilitation effect disappeared when PBM was postponed to 6 h after the last tone (n = 10 each). E PBM decreased tone conditioning ratio when PBM was applied immediately after extinction training (F1, 18 = 4.962, P = 0.029). **P < 0.01, two way ANOVA, PBM vs. Res. Data are mean ± S.E.M.
