Fig. 1: Summary of prevalence rates of suicidal ideation, concentration of sex steroids, and brain volume as a function of age and typical associations between pubertal hormones and brain structures reported the extant literature.

A) Graphical depictions of prevalence rates of suicidal ideation, concentrations of sex steroids, and brain volume as a function of age. Shaded region indicates puberty. The schematized trajectories of gray matter volume adjusted for total brain volume are based on data reported in [162]. B) Summary of typical associations between pubertal hormones and brain structures from both adolescent and adult samples. ACC anterior cingulate cortex, AMYG amygdala, HPC hippocampus, MPFC medial prefrontal cortex, OFC orbitofrontal cortex, STM striatum.