Fig. 1: Proton density MRI: association with CRP. | Molecular Psychiatry

Fig. 1: Proton density MRI: association with CRP.

From: Peripheral inflammation is associated with micro-structural and functional connectivity changes in depression-related brain networks

Fig. 1

A Densities of normalized group mean PD over 376 regions for all cases, all controls, and for high CRP and low CRP subgroups of cases. B From left to right, cortical maps of: PD for all controls, PD for all cases, case-control difference in PD (t -statistic), and no significant case-control differences in PD with PFDR < 0.05. C Left, cortical t -statistic map of association between regional PD and blood CRP concentration, PD~CRP, in all cases and controls combined; right, map of regions where PD~CRP was significantly greater than zero (orange regions), or less than zero (blue regions), with regional PFDR < 0.05. D Left, scatterplot of PD (y-axis) versus CRP (x-axis) for posterior cingulate cortical region v23ab; right, scatterplot of PD versus CRP for dorsolateral prefrontal cortical region, p47r.

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