Fig. 5: Rnd2 deletion affects the intrinsic excitability of adult-born DGNs. | Molecular Psychiatry

Fig. 5: Rnd2 deletion affects the intrinsic excitability of adult-born DGNs.

From: The atypical Rho GTPase Rnd2 is critical for dentate granule neuron development and anxiety-like behavior during adult but not neonatal neurogenesis

Fig. 5

A Representative spiking pattern of control (GFP) and Rnd2-deleted (GFP/Cre) newborn neurons in response to current injection (0 or ± 50 pA for 500 ms). B–D Quantification of the threshold of the first elicited AP (B), the maximum amplitude of this first AP (C) and the maximum AP frequency elicited by current injection (D). Mean ± s.e.m; unpaired two-tailed Student’s t-test; **p < 0.01, ***p < 0.001 (n = 30 neurons from 4 mice in GFP group and n = 17 neurons from eight mice in GFP/Cre group). See also Supplementary Fig. 9.

Back to article page