Table 1 Descriptive statistics of the sample used in this study.

From: Association of brain white matter microstructure with cognitive performance in major depressive disorder and healthy controls: a diffusion-tensor imaging study

 

MDD (N = 482)

HC (N = 525)

Test statistic

P value

Cohen’s d

Age, M ± SD

37.12 ± 13.47

31.68 ± 11.87

t(962.3) = −6.77a

<0.001

0.436

Sex, f/m

311/171

321/204

χ²(1) = 1.23b

0.268

–

IQMVT, M ± SD

113.79 ± 13.71

114.98 ± 13.72

t(1005) = 1.38c

0.170

0.087

Education years, M ± SD

13.15 ± 2.76

13.98 ± 2.42

t(1005) = 5.05c

<0.001

0.329

BDI Sum, M ± SD

17.99 ± 11.19

2.50 ± 2.15

t(505.68) = −29.68a

<0.001

2.640

TMT-A, M ± SD

26.16 ± 10.36

22.52 ± 8.40

t(927.0) = −6.10a

<0.001

0.401

TMT-B, M ± SD

57.12 ± 24.30

46.89 ± 17.30

t(861.5) = −7.64a

<0.001

0.521

DSST, M ± SD

55.97 ± 12.17

65.45 ± 11.05

t(973.2) = 12.9a

<0.001

0.827

RAVLT-S, M ± SD

55.73 ± 9.87

60.15 ± 8.27

t(941.7) = 7.68a

<0.001

0.501

RAVLT-R, M ± SD

13.14 ± 2.99

13.90 ± 1.89

t(799.2) = 4.75a

<0.001

0.336

CBTT-f, M ± SD

8.65 ± 1.84

9.44 ± 1.96

t(1005) = 6.63c

<0.001

0.418

CBTT-b, M ± SD

8.04 ± 1.91

9.00 ± 1.71

t(969.0) = 8.42a

<0.001

0.541

d2, M ± SD

168.05 ± 43.05

194.00 ± 42.86

t(1005) = 9.58c

<0.001

0.604

LNS, M ± SD

15.83 ± 3.20

16.96 ± 3.09

t(1005) = 5.70c

<0.001

0.360

VF-C, M ± SD

23.20 ± 6.01

25.45 ± 5.63

t(1005) = 6.15c

<0.001

0.388

VF-P, M ± SD

11.32 ± 4.22

12.44 ± 4.41

t(1005) = 4.11c

<0.001

0.259

VF-A, M ± SD

15.27 ± 3.48

16.90 ± 3.26

t(1005) = 7.62c

<0.001

0.481

General Cognitive Performance factor, M ± SD

−0.37 ± 1.03

0.34 ± 0.84

t(1005) = −12.04

<0.001

0.935

Number of hospitalizations, M ± SD

1.66 ± 2.16

–

–

–

–

Medication Load Index, M ± SD

1.32 ± 1.43

–

–

–

–

Comorbid diagnosis (yes/no)

203/279

–

–

–

–

  1. BDI Sum beck depression inventory, CBTT-f/b Corsi block-tapping test, forwards/backwards, d2 d2 test of attention, DSST digit symbol substitution test, HC healthy control, IQMVT Intelligence quotient evaluated with the multiple-choice vocabulary test version B (dt. “Mehrfachwahl-Wortschatz-Test Version B”), LNS letter–number–sequences test, M mean, MDD major depressive disorder, RAVLT-S/B Rey Auditory Verbal Learning Test, sum of all correct words/recognition, SD standard deviation, TMT-A/B trail making test, Version A/B, VF-C/P/A verbal fluency test, category/phonemic/alternating.
  2. aTwo-sample t test assuming unequal variance, bPearson χ² test, ctwo-sample t test assuming equal variance.
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