Table 2 Prediction accuracy for specific disorders in patients with at least one diagnosis based on coding variants.

From: Application of deep learning algorithm on whole genome sequencing data uncovers structural variants associated with multiple mental disorders in African American patients

 

Nonsynonymous SNVs

Frameshift SNVs

 

Stop codon

 

Disorder

Precision

Recall

Precision

Recall

Precision

Recall

ADHD

39.4 ± 2.7%

40.5 ± 5.1%

39.8 ± 2.8%

39.1 ± 3.3%

31.3 ± 40.2%

0.08 ± 0.27%

Speech/language disorders

30.3 ± 3.4%

30.6 ± 5.2%

32.6 ± 3.1%

30.9 ± 4.2%

0.0 ± 0.0%

0.0 ± 0.0%

Developmental delays

36.8 ± 2.1%

37.1 ± 4.2%

36.4 ± 2.8%

36.2 ± 4.3%

33.6 ± 1.2%

90.1 ± 1.9%

Depression

25.9 ± 3.1%

23.6 ± 4.4%

26.3 ± 3.4%

24.8 ± 3.6%

19.9 ± 6.5%

3.7 ± 1.5%

Anxiety

18.1 ± 4.1%

13.7 ± 6.1%

20.6 ± 3.4%

18.9 ± 4.1%

15.1 ± 2.3%

14.9 ± 2.9%

ODD

13 ± 11.1%

6.1 ± 5.1%

20.6 ± 5.9%

14.6 ± 4.7%

17.4 ± 9.7%

2.5 ± 1.5%

Autism

11.9 ± 7.1%

6.1 ± 4.8%

15.8 ± 4.5%

13.2 ± 4.6%

11.2 ± 2.6%

12.2 ± 3.4%

Intellectual disabilities

20.3 ± 3.8%

19.4 ± 5.3%

21.4 ± 2.9%

18.8 ± 4.4%

0.0 ± 0.0%

0.0 ± 0.0%

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