Table 3 Prediction accuracy for specific disorders in patients with at least one diagnosis based on non-coding variants.
SNVs in UTR region | SNVs in ncRNA | Intronic SNVs | Intergenic SNVs | |||||
|---|---|---|---|---|---|---|---|---|
Disorder | Precision | Recall | Precision | Recall | Precision | Recall | Precision | Recall |
ADHD | 38.4 ± 2.5% | 33.4 ± 7.3% | 39.6 ± 2.7% | 32.4 ± 5.7% | 39.3 ± 3.6% | 31.1 ± 7.1% | 42.6 ± 2.3% | 42.8 ± 3.9% |
Speech/language disorders | 30.8 ± 3.3% | 31.6 ± 5.8% | 30.1 ± 2.9% | 26.5 ± 5.3% | 30.6 ± 2.8% | 31.8 ± 5.4% | 33.5 ± 2.8% | 33.6 ± 4.5% |
Developmental delays | 35.4 ± 3.5% | 33.5 ± 7.3% | 35.4 ± 2.5% | 38.4 ± 4.5% | 36.6 ± 3.1% | 35.5 ± 4.5% | 36.4 ± 2.4% | 36.8 ± 4.2% |
Depression | 24.1 ± 2.9% | 25.9 ± 7.6% | 24.6 ± 2.8% | 26.9 ± 4.7% | 24.7 ± 3.9% | 24.7 ± 5.5% | 26 ± 3.1% | 26.7 ± 5.0% |
Anxiety | 18.6 ± 3.7% | 17.2 ± 4.2% | 17.2 ± 6.6% | 6.8 ± 3.9% | 16.1 ± 12.3% | 3.8 ± 3.2% | 20.1 ± 4.4% | 17.9 ± 4.4% |
ODD | 10.9 ± 5.5% | 10.3 ± 6.2% | 11.6 ± 4.8% | 9.6 ± 5.5% | 6.8 ± 9.1% | 3.2 ± 2.5% | 15.4 ± 4.4% | 13.5 ± 4.1% |
Autism | 12.9 ± 4.9% | 10.6 ± 5.2% | 13.2 ± 4.8% | 9.5 ± 3.6% | 14.9 ± 7.2% | 7.9 ± 4.2% | 16.9 ± 5.3% | 13.6 ± 4.3% |
Intellectual disabilities | 19.9 ± 3.4% | 14.8 ± 5.3% | 22.1 ± 7.9% | 10.5 ± 5.3% | 21.8 ± 5.8% | 9.8 ± 3.5% | 20.5 ± 2.9% | 22.2 ± 4.4% |
