Fig. 4: Significant decreased default mode subnetwork in UC group compared with HC group. | Molecular Psychiatry

Fig. 4: Significant decreased default mode subnetwork in UC group compared with HC group.

From: Functional brain rewiring and altered cortical stability in ulcerative colitis

Fig. 4

a The circular plot showing the connected brain regions by the network, different networks were colored by different colors and b Surface plot showing the spatial location of the brain regions in the decreased connected component revealed by NBS analysis. c Number of network-to-network connections of the decreased connected component, there are 10 edges (dorsal attention), 13 edges (salience/ventral attention), and 14 edges (control) with DMN regions. d Decreased connected component includes 15 DMN regions, six salience/ventral attention regions, five dorsal attention regions, and five control regions. Vis: visual; som: somatomotor; dor: dorsal attention; s/v.att: salience/ventral attention; lim: limbic; con: control; def: default; tem: temporal parietal. e The logistic regression reveals good discrimination in distinguishing the UC group from HC group using the decreased connected component, ROC curve (AUC = 0.83), TPR True-positive rate; FPR False-positive rate. f The confusion matrix and classification accuracy: 0.77, TPR True-positive rate; FNR False-negative rate. HC Healthy control; UC Ulcerative colitis.

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