Table 2 Results of univariate GLM analysis showing the differences in severity of the sickness symptom complex (SSCseverity) and severe acute respiratory syndrome (SARSseverity) between NLRP3 inflammasome genotypes.

From: In COVID-19, NLRP3 inflammasome genetic variants are associated with critical disease and these effects are partly mediated by the sickness symptom complex: a nomothetic network approach

SNV NLPR3 rs10157379

TT (n = 204)

CT (n = 234)

CC (n = 90)

F

df

p

SARSseverity

4.515 (0.990)

4.679 (0.951)*

4.356 (0.916)

4.07

2/525

0.018

SNV NLPR3 rs10754558

CC (n = 210)

CG (n = 234)

GG (n = 84)

F

df

p

SSCseverity

7.762 (1.680)

7.346 (1.412)**

7.929 (1.670)

6.05

2/525

0.003

  1. *Significantly different from CC (p = 0.007) and significantly different from TT and CC combined (p = 0.011).
  2. **Significantly different from GG (p = 0.004) and CC (p = 0.005).
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