Table 4 Results of binary logistic regression analysis with clinical outcomes as dependent variables.

Depedent Variables	Explanatory variables	β	SE	W	p	OR	%CI	Omnibus model X²	df	p	Nagelkerke pseudo-R²
Fatigue versus no fatigue	Model							35.07	4	<0.001	0.088
	Sex	−0.654	0.186	12.44	<0.001	0.52	0.36–0.75
	NLRP3 rs10754558 CG	−0.626	0.188	11.69	0.001	0.53	0.36–0.76
	Smoking	−1.36	0.642	4.51	0.034	0.26	0.07–0.90
	Hypothyroidism	−1.070	0.453	5.59	0.018	0.34	0.14–0.83
SARS versus no SARS symptoms	Model							150.48	8	<0.001	0.350
	Age	0.372	0.128	8.41	0.004	1.45	1.13–1.87
	SpO2	−0.428	0.118	13.18	<0.001	0.65	0.52–0.82
	CCTA	0.460	0.112	16.84	<0.001	1.58	1.27–1.97
	SSCseverity	−0.680	0.142	22.80	<0.001	0.51	0.38–0.67
	CRP	0.390	0.130	9.04	0.003	1.48	1.15–1.90
	NLRP3 rs10157379 CT	0.445	0.221	4.05	0.044	1.56	1.01–2.41
	NLRP3 rs10754558 GG	1.039	0.301	11.89	0.001	2.83	1.06–5.10
	T2DM	0.541	0.245	4.86	0.028	1.72	1.06–2.78
Moderate + critical	*Model*							345.07	6	<0.001	0.686
	Age	0.870	0.179	23.58	<0.001	2.39	1.68–3.39
	Feritin	0.748	0.175	18.35	<0.001	2.11	1.50–2.98
	SSCseverity	−0.656	0.159	17.15	0.001	0.52	0.38–0.71
	SARSseverity	1.359	0.185	53.87	<0.001	3.89	2.71–5.60
	T2DM	1.011	0.473	4.58	0.032	2.75	1.09–6.94
	Hypertension	0.762	0.361	4.45	0.035	2.14	1.06–4.35
Death vs survival	Model							146.61	8	<0.001	0.424
	Age	1.272	0.208	37.38	<0.001	3.57	2.37–5.37
	SSCseverity	−0.516	0.198	6.82	0.009	0.60	0.41–0.88
	SpO2	−0.627	0.136	21.41	<0.001	0.53	0.41–0.70
	SARSseverity	0.537	0.161	11.17	0.001	1.71	1.25–2.34
	Inflammation	0.388	0.136	8.10	0.004	1.47	1.13–1.93
	BMI	0.330	0.134	6.03	0.021	1.39	1.07–1.81
	T2DM	0.759	0.272	7.76	0.005	2.14	1.25–3.64
	Ferritin	0.314	0.131	5.76	0.016	1.37	1.06–1.77

W Wald Chi-square tests (X²), CI confidence intervals, OR odds ratio.
SpO2 oxygen saturation percentage, CCTA chest computed tomography abnormalities, SSCseverity severity of the sickness symptom complex, SARSseverity severity of severe acute respiratory syndrome, DIIS index first factor extracted from death, intensive care unit admission, orotracheal intubation, and SARS symptoms, CRP C-reactive protein, T2DM type 2 diabetes mellitus, BMI body mass index.

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