Fig. 3: Sex significantly modified the association between CSF Aβ42/40 and Aβ PET. | Molecular Psychiatry

Fig. 3: Sex significantly modified the association between CSF Aβ42/40 and Aβ PET.

From: Age, sex and APOE-ε4 modify the balance between soluble and fibrillar β-amyloid in non-demented individuals: topographical patterns across two independent cohorts

Fig. 3

A, B In ALFA participants, sex significantly modulated the association between CSF Aβ42/40 and Aβ PET uptake indicating higher SUVRs in females women compared to men, in posterior medial regions including the precuneus and the cuneus. Group scatterplot show these interactions in a priori defined progressive ROIs. C, D An overlapping cortical topology was found in ADNI participants indicating the same interaction effects as in ALFA. LL Left lateral, LM Left medial, RL Right lateral, RM Right medial.

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