Fig. 1: Abnormal dynamic connectivity in the AX and PTSD groups during extinction learning.

A Network components showing significant differences in dynamic functional connectivity (FC) between HC and AX groups across multiple networks. Each sphere represents a brain region; the color of the sphere represents its network assignment, and the size of the sphere presents the weighted number of abnormal connections. B Mean FC of the identified network components during extinction learning for the CS+ and CS−. C The proportion of significantly impaired edges within or between the 8 subnetworks. A darkly shaded cell indicates that the connections of that network pair (indexed from x- and y-axis) were extensively impaired. D Distribution of mean connectivity change (ΔFC, comparing late (last 4 trials) minus early (first 4 trials) extinction learning) with each of the 8 subnetworks during CS+ or CS− processing. E–H panels are similar to panels A–D, but for HC vs. PTSD analyses. AX anxiety group, HC healthy controls, PTSD posttraumatic stress disorder.