Fig. 4: Increased striatal GDNF induces gene expression changes in the PFC. See also Supplementary Figs. S4 and S5. | Molecular Psychiatry

Fig. 4: Increased striatal GDNF induces gene expression changes in the PFC. See also Supplementary Figs. S4 and S5.

From: Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia

Fig. 4

A An MA plot showing DE genes (green dots) in the PFC of Gdnf cHyper/cHyper;Nestin-Cre compared to Gdnf wt/wt;Nestin-Cre mice. Selected schizophrenia-related DE genes are highlighted in red. B Top enriched non-redundant GO biological process categories of DE genes in the PFC of Gdnf cHyper/cHyper;Nestin-Cre compared to Gdnf wt/wt;Nestin-Cre mice. C Scatter plot of clusters of top 150 enriched GO biological process categories in Gdnf cHyper/cHyper;Nestin-Cre mice.

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