Fig. 7: GDNF levels are increased in the CSF of first-episode psychosis patients. See also Supplementary Fig. S9. | Molecular Psychiatry

Fig. 7: GDNF levels are increased in the CSF of first-episode psychosis patients. See also Supplementary Fig. S9.

From: Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia

Fig. 7

A Comparison of GDNF in cerebrospinal fluid obtained from 44 healthy controls (HCs) and 69 first-episode psychosis (FEP) subjects, including 29 medication-naive individuals (Non-med.) and 40 individuals with prior exposure to antipsychotics (Med.). NPX, Normalized Protein eXpression (see Methods for details). Mean ± SEM. One-way ANOVA, Tukey’s multiple comparisons test. *p < 0.05. B Correlation between cerebrospinal fluid GDNF levels and the Clinical Global Impression score in 70 FEP subjects. Pearson product-moment correlation.

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