Fig. 5: Impact of mutations in trpγ on longevity, hyperactivity, and sleep. | Molecular Psychiatry

Fig. 5: Impact of mutations in trpγ on longevity, hyperactivity, and sleep.

From: Mutations in trpγ, the homologue of TRPC6 autism candidate gene, causes autism-like behavioral deficits in Drosophila

Fig. 5

a–f Behavior of aged males. a Average longevity of trpγ mutants and controls. b, c Anxiety-like behavior. Average: Distance traveled (b); Time (left) and proportion (right) of time in periphery of arena (c). d–f Average: Sleep duration (d); Duration of sleep episodes (e), and Number of sleep episodes (f). g–l Behavior of aged females. g Average longevity of trpγ mutants and controls. h, i Anxiety-like behavior. Average: Distance traveled (h); Time (left) and proportion of time (right) in periphery of arena (i). j–l Average: Sleep duration (j); Duration of sleep episodes (k), and Number of sleep episodes (l). Genotypes are indicated along the X-axes and color-coded as described in Fig. 1, with the number of animals tested indicated in parenthesis. Statistical significance for (b–d, f, h) is coded as described in Fig. 1. Only the most important statistical differences are shown in the figure. See Supplementary Table 2 for exact values for all comparisons.

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